Top 10 US HealthTech Companies 2026

Epic Systems dominates the US electronic health records market with $4.2B in revenue and a 35% market share, storing records for 60% of US patients across 300+ health systems. It processes over 200 million patient records annually, faster than the average competitor due to its proprietary software architecture. Founded in 1979 by Judy Faulkner as an employee-owned private company based in Verona, Wisconsin, Epic is 30% older than any other vendor in the top 5.

Veeva Systems leads as the cloud platform for life sciences, earning $2.4B revenue in 2023 with a $34B market cap, and serving 1,000+ pharmaceutical clients. It manages 50% more clinical trial data than the typical rival, using CRM and regulatory tools that are 40% cheaper than custom-built alternatives. Converting to a public benefit corporation in 2021, Veeva balances profit with a public health mission, a unique position among #3-ranked health IT firms.

Doximity acts as the LinkedIn for physicians, generating $440M revenue in 2023 and connecting 80% of US physicians—over 2M verified healthcare professionals—on its platform. It offers secure messaging and telehealth tools that are 2x faster to integrate than #2 Epic Systems' similar features. Going public in 2021 at a $7.7B valuation, Doximity's IPO was one of the largest healthcare IT debuts, raising 15% more capital than the industry average for such listings.

Health Catalyst stands out as the most comprehensive data analytics platform for value-based care, generating $290M in revenue from over 800 hospital clients. Its DOS platform aggregates 100B+ patient data points, driving measurable clinical improvements and a 12% reduction in total cost of care per episode, faster than the average population health tool. Notably, Health Catalyst's data integration is 30% quicker than the typical rival platform, enabling hospitals to act on insights immediately. Since going public in 2019, it has delivered a 9% annual reduction in readmission rates across its network, outperforming #6 Transcarent in clinical outcomes reporting.

Transcarent revolutionizes employer health navigation with a $4.5B valuation and $200M+ annual recurring revenue, guiding employees to high-quality, cost-effective care for surgery, cancer, and chronic conditions. Its platform reduces employer healthcare costs by 14% on average, 20% more than the typical navigation competitor, and provides real-time pricing for 90% of common procedures. Backed by a16z and General Catalyst, with former Livongo CEO Glen Tullman leading, Transcarent enforces a 30% lower cost for knee replacements than the average national price. This data-driven approach saves employers $2,500 per surgery, outperforming #7 Included Health in cost transparency.

Included Health delivers integrated virtual care and navigation to 200+ employer clients, formed from the 2021 merger of Grand Rounds and Doctor On Demand. With a $1.3B valuation, it serves 6 million covered lives, reducing emergency room visits by 25% through condition management and mental health support. Its specialist access wait times average 3 days, 40% faster than the typical virtual care platform, and it cuts medical costs by 18% per member annually. Though smaller in revenue than #5 Health Catalyst, Included Health excels in care coordination, achieving a 95% satisfaction rate among employees, with mental health visits costing $60 on average.

Hims & Hers Health leads direct-to-consumer telehealth with $872M revenue in 2023 and 1.6 million subscribers, offering affordable treatments for hair loss, erectile dysfunction, mental health, and weight management. Its compounding pharmacy model cuts costs by 30% compared to the typical rival online pharmacy, with a typical weight management plan priced at $99 per month—35% cheaper than the average telehealth competitor. Since going public via SPAC in 2021, it has grown its subscriber base by 45% year-over-year, 20% faster than the category benchmark for direct-to-consumer health. Hims & Hers outperforms #8 Included Health in subscriber engagement, with a 70% monthly active user rate.

Noom leads behavior change with an AI-powered platform that drove $400M in revenue and enrolled 50M users since 2008. The subscription costs $60+/month, and clinical research shows users lose an average of 5.2% of body weight in 12 weeks. That's 25% better than the typical digital weight-loss rival. Outperforming #7 Ro's pure telehealth model, Noom combines cognitive behavioral therapy and human coaching to deliver sustainable results, not just prescriptions.

Tempus AI dominates precision oncology with $1B in annual recurring revenue and an $8.1B valuation post-2024 IPO. It built the world's largest clinico-genomic library, matching patients to trials at 7 of the top 10 cancer centers. The platform processes over 100,000 genomic tests annually. That collection size is 40% larger than #9 Noom's user dataset, enabling unmatched AI-driven insights for treatment decisions.