The Simpsons (1989)

The Simpsons is the longest-running American animated series, with over 750 episodes across 35+ seasons, redefining animation as a vehicle for social commentary. It launched an entire wave of adult animated comedy, including South Park and Family Guy, and its satirical accuracy correctly predicted 12 major events, from Donald Trump’s presidency to smartwatches. Despite #5 The Wire’s critical acclaim, The Simpsons has influenced more shows, with 65% of animated comedies since 2000 citing it as a direct inspiration. Its budget per episode averaged $4 million by season 30, matching live-action dramas.