Aerobic exercise produces the most robust BDNF increases for neurogenesis and has the strongest evidence for depression treatment, with a 2018 JAMA Psychiatry meta-analysis confirming resistance training alone significantly reduces depressive symptoms. This psychological benefit is amplified by the confidence-building effects of progressive strength gains, offering mental health advantages not replicated by cardio. Notably, the meta-analysis showed resistance training is as effective as aerobic exercise for reducing depressive symptoms, making it a powerful tool for cognitive health.
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