Omega-3 (EPA/DHA Fish Oil)

Omega-3 (EPA/DHA Fish Oil) is essential for daily use due to the typical Western diet's grossly imbalanced omega-6 to omega-3 ratio of 15:1 versus the ideal 2:1, a gap that no other vitamin on this list can correct. Supplementing with 1-2g combined EPA/DHA daily has been validated by the American Heart Association for cardiovascular protection, and the VITAL trial of 25,000 adults found significant reductions in heart attack risk, particularly among those with low fish intake. Compared to #7 (Flaxseed Oil), fish oil provides 3-5 times more bioavailable EPA and DHA, making it 60% more effective at raising blood omega-3 levels than its plant-based rival. This marine-derived supplement also reduces triglycerides by an average of 25% in clinical studies.