Lions Mane Mushroom

Lions Mane is the most well-researched nootropic mushroom with direct evidence for nerve growth factor stimulation. A 2009 double-blind RCT showed significant cognitive improvement in mild cognitive impairment patients after 16 weeks, with effects reversing after stopping confirming causality. Effective dose is 500 to 3000mg of dried mushroom extract daily. Look for fruiting body extracts standardized to over 25 percent beta-glucans.