Glycine-bound magnesium. Activates GABA receptors. $15-25 OTC. Doctors recommend it first.
Magnesium Glycinate outperforms other magnesium forms for sleep, especially glycinate, which crosses the blood-brain barrier more effectively than magnesium oxide or citrate (often used as laxatives). Clinical studies show 200-400mg before bed improves sleep quality in insomniacs, particularly those with restless legs or muscle tension, by activating GABA receptors and reducing neural excitability. Available over the counter for $15-25, it has minimal side effects and is recommended by sleep doctors before prescription options. Data from a 2019 trial indicated 70% of participants reported better sleep within a week, making it 20% more effective than the average sleep supplement.

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