Glycine-bound magnesium. Activates GABA receptors. $15-25 OTC. Doctors recommend it first.
The internet's favorite sleep supplement isn't melatonin — it's magnesium glycinate. Unlike magnesium oxide (which is basically a laxative) or magnesium citrate (which is a gentler laxative), glycinate is bound to the amino acid glycine, which itself has calming properties. The combination crosses the blood-brain barrier more effectively, activates GABA receptors, and reduces neural excitability. Studies show 200-400mg before bed improves sleep quality in people with insomnia, particularly those with restless legs or muscle tension. It's available over the counter for $15-25, has minimal side effects, and is the supplement sleep doctors recommend most often before reaching for prescription options.

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