"One Dance" — Drake ft. WizKid & Kyla

Over 3.2 billion streams. Drake's Afrobeats-influenced track spent 15 weeks at #1 on the Hot 100 in 2016. It was the first song to reach 1 billion streams on Spotify and introduced mainstream Western audiences to the dancehall/Afrobeats fusion that would dominate pop for the next decade. Source: Spotify Charts.