AI mental health chatbots Woebot and Wysa collectively reached 6 million users in 2025, delivering CBT (cognitive behavioral therapy)-based interventions for anxiety and depression at a fraction of human therapist costs. NIH-funded studies showed users of Woebot experienced a 22% reduction in PHQ-9 depression scores after 2 weeks β comparable to short-term outcomes from human therapy for mild-to-moderate depression.

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