The Last Supper is the most audacious experimental fresco in history, its tempera-and-oil technique causing deterioration within 20 years of completion yet captivating 1,500 daily ticketed visitors. Leonardo da Vinci's 1495-98 mural in Milan survived wartime bombing and centuries of neglect to become a UNESCO World Heritage Site in 1980. It attracts 20% fewer annual visitors than The Birth of Venus but commands higher ticket prices at €12 per person, reflecting its exclusive timed-entry system.

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