Action Comics #1 — $3.25 million (2021)

Action Comics #1, featuring Superman's debut in 1938, set a record at $3.25 million in a 2021 Heritage Auctions sale—the most ever for a comic book. Only about 100 copies survive from the original print run, and this CGC 8.5-graded example is the finest regularly traded Superman #1, towering above a typical high-grade comic. Its price is less than half the $7.25 million of the Honus Wagner card at #5, yet it remains a cornerstone of pop culture and comic collecting.