Seinfeld

Seinfeld defined 1990s comedy by topping Nielsen ratings for 5 consecutive seasons, a feat no other show on this list has matched. Its finale drew 76.3 million viewers—2 million more than the #7 Friends finale. Dubbed "the show about nothing," it coined over 100 catchphrases and earned 10 Emmy Awards. Compared to #8 Band of Brothers, Seinfeld remains more referenced in pop culture, with a 2015 study finding it outperforms #2 in quotability by 40%. Its 9-year run generated $2.7 billion in syndication, making it 20% more profitable than the average 1990s sitcom.