Mediterranean Diet Pattern

The Mediterranean diet is the single most studied dietary pattern for chronic inflammation reduction. A 2018 NEJM trial of 7447 high-risk patients showed 30 percent reduction in major cardiovascular events compared to low-fat diet. The PREDIMED trial showed 30 to 40 percent reductions in inflammatory markers CRP and IL-6 at 12 months. Not a restriction diet but an eating pattern centered on olive oil, vegetables, legumes, fish, and moderate red wine.