The Oprah Winfrey Show

The Oprah Winfrey Show remains the most influential talk show in history, having run for 25 years and built a billion-dollar brand. On average, 15 million viewers tuned in daily, and the show’s book club turned 70 titles into instant bestsellers, including classics like *Falling*. This reach outperforms #2’s cultural impact, as Oprah’s interviews—such as Tom Cruise’s couch jump—generated over 1 billion media impressions, far more than Carson’s most viral moments.