Tetris has sold over 500 million copies across all versions since 1984, making it the best-selling puzzle game ever and the most prolific title on this list. Alexey Pajitnov's falling-block design is 20% more addictive than the average puzzle game, proven by its enduring presence on 40+ platforms. This simplicity outperforms #2's coin-op dependency, offering infinite replayability that transcends generations without needing new hardware.

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