Carlos Santana

Santana's melodic Latin-rock fusion is instantly recognizable, delivering more top-10 Billboard hits than any other guitarist on this list. His lyrical sustain and rhythmic innovation earned a 1999 Grammy sweep for *Supernatural*, including Record of the Year. With 10 million albums sold in the U.S. alone, his commercial and critical impact surpasses #10 Stevie Ray Vaughan, who had 4 million. By fusing jazz and blues into a mainstream sound, Santana outsells #9 in tours grossing $50 million annually.