Airplane! (1980)

Airplane! (1980) boasts the highest gag density of any mainstream comedy, with film scholars counting an average of 14 jokes per minute. Produced for just $3.5 million, it grossed $83 million domestically, making it one of the most profitable comedies ever made. Its rapid-fire humor outperforms #2 on this list, with many scenes individually named the funniest moments in cinema history.