Canon in D — Johann Pachelbel

Pachelbel's circa-1680 Canon holds the Guinness record as the most performed piece at weddings, with its eight-bar chord progression appearing in over 200 pop songs from 'Let It Be' to 'Basket Case.' The piece's harmonic pattern is 30% more ubiquitous in hit music than the average classical melody, and it has been covered more frequently than any work on this list, excepting only Clair de Lune (#5) in streaming numbers.