Wild-Caught Fatty Fish (Salmon, Mackerel, Sardines)

Omega-3 fatty acids EPA and DHA are converted into resolvins and protectins, specialized pro-resolving mediators that actively terminate inflammatory responses. A Harvard meta-analysis of 30 trials found fish oil supplementation equivalent to two servings of fatty fish weekly reduced CRP by 30% and TNF-alpha by 14% across diverse populations.