Extra Virgin Olive Oil

The cornerstone of the Mediterranean diet contains oleocanthal, a phenolic compound that inhibits COX-1 and COX-2 enzymes with a mechanism identical to ibuprofen. The PREDIMED trial of 7,447 participants found that 4+ tablespoons daily of EVOO reduced cardiovascular events by 30% and significantly lowered C-reactive protein, IL-6, and other inflammatory biomarkers.