Chris Sacca turned a cabin in Lake Tahoe into a launchpad for unicorns. After leaving Google, he angel-invested in Twitter, Uber, Instagram, and Kickstarter—a run that earned his Lowercase Capital fund a reported 250x return, making it the best-performing venture fund of its vintage. That figure is 60% higher than the average top-decile venture fund's lifetime multiple. Sacca's Instagram check alone was returned as a $78 million gain after Facebook's acquisition, outperforming #7's single-best deal by more than $20 million. A master of early, concentrated bets.

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