U.S. Route 66 or U.S. Highway 66 was one of the original highways in the United States Numbered Highway System. Established on November 11, 1926, with signage erected the following year, the highway ran from Chicago, Illinois, through Missouri, Kansas, Oklahoma, Texas, New Mexico, and Arizona before terminating in Santa Monica, California, covering 2,448 miles (3,940 km).

Contender: Route 66 (Chicago to Santa Monica)
Contender: Route 66 (Chicago to Santa Monica)
Contender: Route 66, USA
Ranked #2 on "Top 10 Best Road Trips in America". Cast your vote to back or challenge this spot.
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